Crewe is a railway town and civil parish in the unitary authority of Cheshire East in Cheshire, England. The Crewe built-up area had a total population of 75,556 in 2011, which also covers parts of the adjacent civil parishes of Willaston, Shavington cum Gresty and Wistaston.

Crewe is perhaps best known as a large railway junction and home to Crewe Works; for many years, it was a major railway engineering facility for manufacturing and overhauling locomotives, but now much reduced in size. From 1946 until 2002, it was also the home of Rolls-Royce motor car production. The Pyms Lane factory on the west of the town now exclusively produces Bentley motor cars. Crewe is 158 miles (254 km) north of London and 28 miles (45 km) south of Manchester city centre. 

Although the name Creu first appears in the Domesday Book, the modern urban settlement of Crewe was not formally planned out until 1843 by Joseph Locke to consolidate the "railway colony" that had grown up since around 1840–41 in the area near to the railway junction station opened in 1837, even though it was called Crewe by many, from the start. Crewe was thus named after the railway station, rather than the other way round. The name derives from an Old Welsh word 'criu', meaning 'weir'.